Aid Overall Health

L-Serine is a non-essential amino acid that is made by the body to create proteins for the growth of tissue and metabolism of fat. It is also present in RNA and DNA ( your genes), and ADP and ATP which are the blocks of energy the body creates from food to support the functions of cells, muscles and organs.

L-Serineis an ingredient found in many nutritional supplements that are used to promote brain stimulation and enhancement, to increase immunity and to improve moods and anxiety levels. L-Serine is also added to supplements that are directed towards weight loss and increased metabolism. 

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L-Serine in Foods L-Serine is made naturally by the body, but it is also found in an array of foods as it is used in the production of proteins in many animals. Foods containing L-Serine include meats, dairy, legumes and soy. History or L-Serine L-Serine and its components were ori... more

L-Serine in Foods

L-Serine is made naturally by the body, but it is also found in an array of foods as it is used in the production of proteins in many animals. Foods containing L-Serine include meats, dairy, legumes and soy.

History or L-Serine

L-Serine and its components were originally derived for supplements from the brains of cows. With the dangers associated with the increase in Bovine Spongiform Encephalopathy, or Mad Cow Disease, L-Serine is currently derived from soy products.

There have been no reports in a difference in function between the L-Serine derived from cows and that derived from soy sources.

L-Serine in Brain Supplements

Forms of L-Serine are found in many supplements that are touted to improve memory, focus and cognitive function. Dr. Andrew Weil, M.D., recommends serine to boost brain function at, along with mental strength-training and daily exercise.

L-Serine is an amino acid that helps to build cell membranes, thus improving the functions of the brain. L-Serine makes up the most common phospholipid found in the brain as it is present in the membranes covering the nerves of the brain.

L-Serine and Depression

L-Serine is one of the first ingredients in a long recipe that eventually ends with the chemical serotonin. Serotonin is a chemical in the brain that is linked with feelings of happiness and wellbeing. Low levels of serotonin have been connected to depression, anxiety and loss of appetite.

Conventional wisdom follows that an increase in the levels of L-Serine will lead to increases in serotonin, and thus L-Serine supplements will be successful at improving moods and feelings of anxiety.

L-Serine and Sports

L-Serine has also been found to be useful in supplements that improve the body’s functions for athletic sports. The Journal of the International Society of Sports Nutrition, has listed findings of L-Serine improving muscle performance and recovery as well as alleviating the mental stress that accompanies strenuous activities.

L-Serine and Weight Loss

L-Serine is also added to many nutritional supplements, along with other amino acids, that are taken to promote energy and increased metabolism for fat-burning and weight loss.

L-Serine and Studies With the Brain

Many researchers are investigating the usefulness of L-Serine in improving the mental function of sufferers of Alzheimer’s disease and dementia, hoping that L-Serine might be used to treat patients with Alzheimer’s disease and dementia as well as prevent diseases such as Alzheimer’s and dementia from occurring in the first place.

Studies are also being conducted in using L-Serine and its counterparts to treat Attention Deficit Hyperactivity Disorder.

L-Serine and Other Uses

L-Serine is a common component found in moisturizers and skin cosmetics as it is a required building block for cell membranes that help to keep skin looking young and healthy.

L-Serine Side Effects

As L-Serine is a naturally-occurring amino acid in the body, there are few side effects reported with taking supplements that contain L-Serine. Side effects that have been reported are nausea, heartburn and sleeplessness.

A high level of L-Serine is undesirable as it would compromise the body’s natural balances; always follow the manufacturer’s recommended dosages for any supplement or medication.

L-Serine and Medical Conditions

While L-Serine is undergoing testing to aid in the fighting of many diseases and conditions, there are few medical conditions that restrict the intake of L-Serine.  Pregnant and nursing women should not take L-Serine unless instructed by a doctor. Likewise, children and teens under the age of 18 should not use L-Serine unless instructed by a physician.

L-Serine Supplementation

L-Serine is added to many nutritional and dietary supplements in pill form, or it is offered as a 500mg pill. It is also sold in its crystalized, pure form, which should still be taken orally. Only a physician should administer L-Serine in any way that is not given orally.

Consult with your doctor or physician before starting any medication or supplement, and always follow the manufacturer’s instructions as closely as possible. Use the supplement finder to help boost your brain power and muscle performance by finding L-Serine right now!


  • Side Effects
  • Other Names
  • Uses
BC-PS, Bovine Cortex Phosphatidylserine, Bovine Phosphatidylserine, Fosfatidilserina, LECI-PS, Lecithin Phosphatidylserine, Phosphatidylsérine, Phosphatidyl Serine, PS, PtdSer, Soy-PS, Soy Phosphatidylserine
Brain Activity
Brain Function
Brain Health
Weight Loss